Has anyone heard of RhoGAM not being effective? how does that affect your 2nd pregnancy?

I had the same problem and am now 6 months pregnant with my second and my pregnancy is completely normal. As long as your doctor is aware of the issue they can monitor you throughout your pregnancy and make sure your baby is safe and your pregnancy is normal. I have been told that it can cause difficulties in conceiving but I got pregnant on birth control, there really was no problem there lol. From what I was told by my doctor, RhoGam is used as a preventative measure. Your body COULD view any subsequent babies as a parisite, but it doesn't mean it WILL. I wouldn't stress too much about it- as long as you have a doctor you trust, should you decide to have another baby, they can help you with any concerns you may have.